samtools: samtools (Sequence Alignment/Map Tools) samtools: samtools: SAM (Sequence Alignment/Map) format is a generic format for storing samtools: large nucleotide sequence alignments. The original samtools package samtools: has been split into three separate but tightly coordinated projects: samtools: htslib (C-library for handling high-throughput sequencing data), samtools: samtools (for handling SAM, BAM, CRAM), and bcftools (for handling samtools: VCF and BCF). samtools: samtools: Homepage: http://www.htslib.org samtools: